Time for a mini end-of-year review. So, what were the highlights of 2025 at E-Phys? After 11 years in the School of Medicine in Clermont-Ferrand, our lab moved in early January to a more remote (and glamorous) dedicated site in the countryside. The transition was smooth, and we greatly appreciate our new working environment, which combines ease of use, safety, and strict compliance with regulations governing the use of animals for scientific research.
On the scientific front, we revisited the activity-dependent slowing of conduction velocity in unmyelinated nociceptors in both rats and mice, using single-unit recordings at the level of the dorsal root ganglia (see this year’s SfN poster). We also established rodent equivalents of the cold pressor test in mice and rats. Together, these assays place us in a strong position to evaluate the activity of Nav1.8 channel blockers on an electrophysiological basis.
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Meanwhile, E-Phys wishes to all our past and future customers a happy end of year.